Making a Semax or Selank nasal spray

• Your lyophilized (freeze-dried) Semax or Selank vial
• Bacteriostatic water — not sterile or distilled. The benzyl alcohol in BAC water is a preservative, which matters for something you’ll use over a couple of weeks.
• A metered fine-mist nasal spray bottle (an amber glass one is ideal). Find its volume per spray — vendor spec, or fill volume ÷ number of sprays it delivers. Most are around 0.1 mL.
• An insulin syringe (to measure water and transfer the solution) and alcohol swabs

Decide your concentration before you add water, so that one or two sprays land on your dose. The math is simple: the peptide spreads evenly through the water, and each spray delivers a fixed slice of that volume.

Semax example: a 30 mg vial in 10 mL of BAC water is 3 mg/mL. At ~0.1 mL per spray, that’s ~300 mcg per spray — so one spray is a standard dose.

Selank example: a 10 mg vial in ~3.3 mL is also 3 mg/mL → ~300 mcg per spray. Prefer 200 mcg sprays? Use 5 mL instead (2 mg/mL → ~200 mcg), and run one or two sprays per dose.

1. Clean up. Wash your hands; wipe the vial stopper and the spray bottle’s parts with an alcohol swab and let them dry.
2. Measure the water. Draw your calculated volume of bacteriostatic water with the insulin syringe.
3. Reconstitute gently. Add the water slowly down the inside wall of the vial — don’t blast it directly onto the powder. Swirl gently to dissolve; never shake. Wait until it’s fully clear.
4. Transfer. Draw the solution back up and dispense it into the nasal spray bottle. (If the powder shipped in a small vial, doing the dissolving in the vial first keeps it cleaner than pouring powder into the bottle.)
5. Prime the pump. Pump several times into a tissue until it throws a fine, even mist. Priming uses a little solution — fill with that in mind.
6. Label it. Write the compound, the concentration (mg/mL), the mcg per spray, and the date on the bottle.

One actuation per nostril is the usual unit. Using the Semax example above (~300 mcg/spray), a single spray in one nostril is ~300 mcg; one in each nostril is ~600 mcg. Tip your head slightly forward, aim toward the outer wall of the nostril (not the septum), breathe in gently as you spray, and don’t sniff hard — you want it to land on the tissue, not run down your throat. A little goes a long way; let it absorb.

Keep it in the fridge. Reconstituted with bacteriostatic water, peptides like these are generally treated as good for a few weeks refrigerated — the common rule of thumb is up to about 28 days, the working life of the benzyl alcohol preservative. Keep it out of light, don’t freeze a glass sprayer, and throw it out if the solution turns cloudy or anything floats in it. The date on the label is what keeps you honest.

• Nasal irritation is the common complaint — a brief sting or dryness. It tracks with the route, not the molecule, and usually settles.
• Purity matters more here, not less. This route is direct — insist on a certificate of analysis or third-party test before running anything you’ll spray into your head.
• One bottle, one person. A nasal sprayer touches mucous membranes; don’t share it.
• It’s still not medical advice. The evidence behind Semax and Selank is thin and mostly Russian-language — see each peptide’s page for the honest read before you decide anything.